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A Laboratory Exercise for Genotyping Two Human Single Nucleotide Polymorphisms
Michael mccarthy - Personal Name
James Fernando - Personal Name
Bradley Carlson - Personal Name
Timothy LeBard - Personal Name
Finianne Umali - Personal Name
Bryce Ashton - Personal Name
Ferrill F. Rose Jr. - Personal Name
The dramatic decrease in the cost of sequencing a human genome is leading to an era in which a wide
range of students will benefit from having an understanding of human genetic variation. Since over 90%
of sequence variation between humans is in the form of single nucleotide polymorphisms (SNPs), a
laboratory exercise has been devised in order to illustrate the importance of SNPs. Two separate SNPs
are analysed, one of which has a significant effect on a person’s phenotype and one which does not.
The genotyping protocol is relatively inexpensive and uses standard molecular biology reagents and
equipment.
range of students will benefit from having an understanding of human genetic variation. Since over 90%
of sequence variation between humans is in the form of single nucleotide polymorphisms (SNPs), a
laboratory exercise has been devised in order to illustrate the importance of SNPs. Two separate SNPs
are analysed, one of which has a significant effect on a person’s phenotype and one which does not.
The genotyping protocol is relatively inexpensive and uses standard molecular biology reagents and
equipment.
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Informasi Detil
Judul Seri
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No. Panggil
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Penerbit
Routledge : Taylor & Francis; Routledge., 2016
Deskripsi Fisik
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Bahasa
English
ISBN/ISSN
0021-9266
Klasifikasi
NONE
Informasi Detil
Tipe Isi
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Tipe Media
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Tipe Pembawa
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Edisi
2016 Vol. 50, No. 1, 73–85
Subyek
Info Detil Spesifik
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Pernyataan Tanggungjawab
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